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The insufflation of cocaine crystals may also cause physical trauma to epithelial cells, leading to inflammatory lesions, which may also worsen due to the tendency for patients to physically remove the scabs produced in the damaged tissue, which induces further mechanical damage. [6] Cocaine is capable of inducing apoptosis of epithelial cells ...
Levamisole has become a common additive to illicit cocaine. It is thought to intensify the "high" by releasing dopamine in the brain, acts as a bulking agent, and is a difficult adulterant to recognize. Potential risks of levamisole-laced cocaine include neutropenia, agranulocytosis, arthralgias, retiform purpura, skin necrosis, and fever.
This nerve damage causes an individual to experience pain and motor weakness, first in the feet and hands and then progressing centrally. Alcoholic polyneuropathy is caused primarily by chronic alcoholism ; however, vitamin deficiencies are also known to contribute to its development.
The treatment of peripheral neuropathy varies based on its cause, and treating the underlying condition can help neuropathy treatment. When peripheral neuropathy results from diabetes mellitus or prediabetes, blood sugar management is key to treatment. In prediabetes, strict blood sugar control can significantly alter the course of neuropathy. [31]
Diagnostic pathways are imperative to assess the status and extent of deformities, evaluate nerve function, and visualise damage. These pathways can involve nerve testing, physical examinations, lab tests, and imaging examinations. Current treatments for hand deformities can be classified by non-surgical or surgical methods.
Dysesthesia, along with polyneuropathy can be a symptom of nerve damage caused by Lyme disease. [4] The dysesthetic sensations continue after the successful antibiotic treatment of Lyme disease. Dysesthesia is a common symptom of a withdrawal from alcohol or other drugs. Dysesthesia is also a common symptom of multiple sclerosis. It is an ...
Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...
In order to assist and improve in sensory nerve damage, which can be difficult to maintain without medication, some patients adopt behavioural strategies in order to manage chronic pain, along with emotional discrepancies that may follow the nerve injury (national institute of neurological disorders).