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The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...
H 1-antihistamines work by binding to histamine H 1 receptors in mast cells, smooth muscle, and endothelium in the body as well as in the tuberomammillary nucleus in the brain. Antihistamines that target the histamine H 1 -receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and sneezing).
H 1-antihistamines can be administered topically (through the skin, nose, or eyes) or systemically, based on the nature of the allergic condition. The authors of the American College of Chest Physicians Updates on Cough Guidelines (2006) recommend that, for cough associated with the common cold, first-generation antihistamine-decongestants are ...
The recommended dosage of Benadryl tablets for adults is 1 to 2 tablets every 4 to 6 hours, [1] and only 1 tablet every 4 to 6 hours for children under the age of 12. [2]The Benadryl challenge is an internet challenge that emerged in 2020, revolving around the deliberate consumption, excessive use and overdose of the antihistamine medicine diphenhydramine (commonly sold in the United States ...
Modafinil is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It is often used off-label as a nootropic. Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for ...
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
It takes 60- to 80-mph winds for the company to shut down transmission lines. CEO Steve Powell said it didn't see winds that powerful.
[1] [2] Yale physiologist John Farquhar Fulton encouraged them to publish the work for a broader audience and introduced them to a publisher at the Macmillan Publishing Company. [1] Their new text was first published in 1941 under the title The Pharmacological Basis of Therapeutics: A Textbook of Pharmacology, Toxicology and Therapeutics for ...