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Image-guided surgery based on MRI is used to guide prostatic biopsy. [7] Image guidance is used to assist surgeons with identifying anatomic landmarks and surgical planes between the prostate and neurovascular bundles during nerve-sparing procedures. [7]
Deep neurovascular bundles, which often include arteries, have a more complicated structure than superficial neurovascular bundles. Since arteries have high intraluminal blood pressure relative to capillaries and veins, these bundles have smooth muscle and connective tissue structures outside the endothelium. This structure allows arteries to ...
Micrograph showing a prostate cancer (conventional adenocarcinoma) with perineural invasion. H&E stain. In pathology, perineural invasion, abbreviated PNI, refers to the invasion of cancer to the space surrounding a nerve. It is common in head and neck cancer, prostate cancer and colorectal cancer.
To try and overcome current capacity issues with MRIs for prostate cancer, they have now set up the PRIME trial to explore whether a shorter and cheaper MRI scan could become the new standard of care.
The prostate is the only male accessory gland that occurs in cetaceans, [68] consisting of diffuse urethral glands [69] surrounded by a very powerful compressor muscle. [70] The prostate gland originates with tissues in the urethral wall.
Using IRE, the urethra, bladder, rectum and neurovascular bundle and lower urinary sphincter can potentially be included in the treatment field without creating (permanent) damage. [citation needed] IRE has been in use against prostate cancer since 2011, partly in form of clinical trials, compassionate care or individualized treatment approach.