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Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. [2] Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. [2] [5] Atopic dermatitis results in itchy, red, swollen, and cracked skin. [2]
Stasis dermatitis, allergic contact dermatitis, acute irritant contact eczema and infective dermatitis have been documented as possible triggers, but the exact cause and mechanism is not fully understood. [7] Several other types of id reactions exist including erythema nodosum, erythema multiforme, Sweet's syndrome and urticaria. [3]
Allergic diseases are clinical manifestations of such inappropriate, atopic responses. [ 2 ] Atopy may have a hereditary component, although contact with the allergen or irritant must occur before the hypersensitivity reaction can develop (characteristically after re-exposure ). [ 3 ]
The allergic march (also called atopic march) is a medical term used to explain the natural history of atopic manifestations. The allergic march is characterized by some antibody responses to immunoglobulin E (IgE) and clinical symptoms that may appear in childhood, and continue for years or decades and often changing with age. [1]
Allergic/contact dermatitis or atopic dermatitis As above. Eosinophils may be present in the dermis and epidermis (eosinophilic spongiosis). [2] Allergic dermatitis Atopic dermatitis Seborrheic dermatitis Typical findings: [5] Focal, usually mild, spongiosis with overlying scale crust, with a few neutrophils; The crust is often centered on a ...
The Rocatinlimab Phase 3 rocket program in atopic dermatitis is progressing with additional data expected throughout 2025. These studies will provide deeper insight into Rocatinlimab's profile.
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