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Acetylcholine (ACh) is an organic compound that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. [1] Its name is derived from its chemical structure: it is an ester of acetic acid and choline. [2] Parts in the body that use or are affected by acetylcholine are referred to as cholinergic.
Choline is a precursor to acetylcholine, a neurotransmitter that plays a necessary role in muscle contraction, memory and neural development. [2] [3] [5] Nonetheless, there is little acetylcholine in the human body relative to other forms of choline. [4]
The following outline is provided as an overview of and topical guide to human anatomy: Human anatomy is the scientific study of the morphology of the adult human. It is subdivided into gross anatomy and microscopic anatomy. Gross anatomy (also called topographical anatomy, regional anatomy, or anthropotomy) is the study of anatomical ...
Gross anatomy has become a key part of visual arts. Basic concepts of how muscles and bones function and deform with movement is key to drawing, painting or animating a human figure. Many books such as Human Anatomy for Artists: The Elements of Form, are written as a guide to drawing the human body anatomically correctly. [4]
When ligands bind to the receptor, the ion channel portion of the receptor opens, allowing ions to pass across the cell membrane.. Acetylcholine is a neurotransmitter synthesized from dietary choline and acetyl-CoA (ACoA), and is involved in the stimulation of muscle tissue in vertebrates as well as in some invertebrate animals.
Choline acetyltransferase was first described by David Nachmansohn and A. L. Machado in 1943. [6] A German biochemist, Nachmansohn had been studying the process of nerve impulse conduction and utilization of energy-yielding chemical reactions in cells, expanding upon the works of Nobel laureates Otto Warburg and Otto Meyerhof on fermentation, glycolysis, and muscle contraction.
End plate potentials are produced almost entirely by the neurotransmitter acetylcholine in skeletal muscle. Acetylcholine is the second most important excitatory neurotransmitter in the body following glutamate. It controls the somatosensory system which includes the senses of touch, vision, and hearing.
Various bones of the human skeletal system. The axial skeleton , comprising the spine, chest and head, contains 80 bones. The appendicular skeleton , comprising the arms and legs, including the shoulder and pelvic girdles, contains 126 bones, bringing the total for the entire skeleton to 206 bones.