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2. Is It Safe to Take Cialis Daily? - AOL

   www.aol.com/safe-cialis-daily-115900442.html

   Cialis’s long duration of action has earned it the nickname as the “weekend” pill for dealing with ED; while most people are familiar with the original 10 and 20mg Cialis tablets that can ...

3. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

   www.aol.com/cialis-side-effects-expect-avoid...

   Tadalafil 20-milligram side effects are often more noticeable than 10-milligram or 5-milligram side effects when it comes to acid reflux and indigestion. Adjusting your dosage might help keep the ...

4. What Is the Safest ED Medication? - AOL

   www.aol.com/safest-ed-medication-105700669.html

   The active ingredient in Cialis, tadalafil is a long-lasting ED drug that offers relief from ED for up to 36 hours per dose — a duration of action that’s earned it the nickname, the “weekend ...

5. Tadalafil - Wikipedia

   en.wikipedia.org/wiki/Tadalafil

   Although sildenafil, vardenafil, and tadalafil all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.5 hours), [21] compared to sildenafil and vardenafil, which are both 4–5 hours. [22] This translates to a longer duration of action, which is partly responsible for "The Weekend Pill" nickname.

6. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

   www.aol.com/4-common-ed-pills-weighing-141800609...

   This makes tadalafil a great choice if you want to get aroused more than once a day, or only want to take one pill over the course of an entire weekend. Another advantage of tadalafil is that it ...

7. Eli Lilly and Company - Wikipedia

   en.wikipedia.org/wiki/Eli_Lilly_and_Company

   In 2003, Eli Lilly and Company introduced Cialis (tadalafil), a competitor to Pfizer's blockbuster Viagra for erectile dysfunction. Cialis maintains an active period of 36 hours, causing it sometimes to be dubbed the "weekend pill". Cialis was developed in a partnership with biotechnology company Icos Corporation. In December 2006, Lilly bought ...

8. Sex and drugs - Wikipedia

   en.wikipedia.org/wiki/Sex_and_drugs

   While Phosphodiesterase-5 (PDE5) inhibitors such as sildenafil, tadalafil, vardenafil, and avanafil are primarily known for treating erectile dysfunction, it also has a positive effect on libido. [67] Flibanserin is a drug that is both a serotonin antagonist and agonist that treats hypoactive sexual desire disorder (HSDD) for premenopausal women.

9. Cialis vs. Viagra: How Are They Different? - AOL

   www.aol.com/cialis-vs-viagra-different-175700354...

   Tadalafil or generic Cialis can be taken either on demand or as a daily ED medication. ... Put simply, Cialis works like a weekend pill for ED, hence its nickname, while Viagra is more of an ...