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Bipolar on average, starts during adulthood. Bipolar 1, on average, starts at the age of 18 years old, and Bipolar 2 starts at age 22 years old on average. However, most delay seeking treatment for an average of 8 years after symptoms start. Bipolar is often misdiagnosed with other psychiatric disorders.
Onset of Bipolar Disorder. Signs of bipolar disorder generally emerge in young adulthood. Research suggests that 70 percent of people with bipolar disorder experience their first manic episode ...
Limbic hypermetabolism is more consistent than in bipolar depression, but the overall study quality is low due to limitations associated with neuroimaging in acutely manic patients. [70] Another review reported that mania is generally associated with frontal/ventral hypoactivation, while depression is generally associated with the opposite.
The trouble that researchers have had in conclusively identifying genes that cause bipolar disorder has led them to search for an epigenetic component to bipolar disorder. Epigenetics is the study of heritable phenotypes that occur without changes to the primary DNA sequence. Typically, epigenetics focuses on the expression and regulation of genes.
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The polar opposite of the manic side of bipolar disorder are the periods of depression, often severe or “major” depression that can cause significant problems at work, school, home and in ...