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Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests as part of the CBC. Since the average platelet size is larger when the body is producing increased numbers of platelets, the MPV test results can be used to make inferences about platelet ...
EDTA-dependent agglutination. In some individuals, clinically insignificant antibodies may cause in vitro agglutination of platelets. As a result of platelet clumping, platelet counts reported by automated counters may be much lower than the actual count in the blood because these devices cannot differentiate platelet clumps from individual cells.
Low levels of platelets in turn may lead to prolonged or excessive bleeding. It is the most common coagulation disorder among intensive care patients and is seen in a fifth of medical patients and a third of surgical patients. [3] A normal human platelet count ranges from 150,000 to 450,000 platelets/microliter (μL) of blood. [4]
Giant platelet disorders can be further categorized: [6] caused by auto-immune disorders, for example Immune thrombocytopenic purpura (ITP), and characterized by low platelet count, but high MPV (mean platelet volume). [7] Caused by glycoprotein abnormalities: Bernard–Soulier syndrome, velocardiofacial syndrome
Feline infectious anemia (FIA) is an infectious disease found in felines, causing anemia and other symptoms. The disease is caused by a variety of infectious agents, most commonly Mycoplasma haemofelis (formerly called Haemobartonella before Haemobartonella and Eperythrozoon species were reclassified as mycoplasmas).
High platelet counts can occur in patients with polycythemia vera (high red blood cell counts), and is an additional risk factor for complications. [ citation needed ] A very small number of people report symptoms of erythromelalgia , a burning sensation and redness of the extremities that resolves with cooling, or aspirin or both.
Within three hours, his platelets dropped to dangerously low levels and he experienced a seizure. [2] His platelet count remained extremely low for four days, finally returning to normal levels by the fifth day. [2] Bone marrow biopsy from Harrington's sternum demonstrated normal megakaryocytes, the cells necessary for platelet production. [2]
Mean platelet volume, in blood testing, a measure of platelet size; Meerwein–Ponndorf–Verley reduction, a chemical reaction reducing ketones and aldehydes; Monkeypox virus, a pathogen of humans and other euarchontoglires