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Class IV agents affect calcium channels and the AV node. Class V agents work by other or unknown mechanisms. With regard to management of atrial fibrillation, classes I and III are used in rhythm control as medical cardioversion agents, while classes II and IV are used as rate-control agents.
[1] [2] [3] Subgroup C01 is part of the anatomical group C Cardiovascular system. [4] Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QC01. [5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.
Class of medications that are competitive antagonists that block the receptor sites for the endogenous catecholamines epinephrine (adrenaline) and norepinephrine (noradrenaline) on adrenergic beta receptors, of the sympathetic nervous system.
Sodium channel blockers (1 C, 77 P) Pages in category "Antiarrhythmic agents" The following 59 pages are in this category, out of 59 total.
Lorcainide (Lorcainide hydrochloride) is a Class 1c antiarrhythmic agent that is used to help restore normal heart rhythm and conduction in patients with premature ventricular contractions, ventricular tachycardiac [1] and Wolff–Parkinson–White syndrome. [2]
Moracizine [1] or moricizine, sold under the trade name Ethmozine, is an antiarrhythmic of class IC. [2] It was used for the prophylaxis and treatment of serious and life-threatening ventricular arrhythmias, [3] but was withdrawn in 2007 for commercial reasons. [4]
Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances. [1] It is a diastereomer of antimalarial agent quinine, [2] originally derived from the bark of the cinchona tree. The drug causes increased action potential duration, as well as a prolonged QT interval. As of 2019, its IV formulation is no longer being ...
The second Cardiac Arrhythmia Suppression Trial (CAST II) modified the enrollment criteria to include patients at higher risk for serious arrhythmia. [4] This included 1) patients enrolled within 4 to 90 days of a previous MI, 2) a left ventricular ejection fraction lower than 40%, 3) prior to enrollment, suppression of PVCs had occurred with the drugs (vs. placebo) using a double-blinded ...