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  2. HELLP syndrome - Wikipedia

    en.wikipedia.org/wiki/HELLP_syndrome

    HELLP syndrome is a complication of pregnancy; the acronym stands for hemolysis, elevated liver enzymes, and low platelet count. [1] It usually begins during the last three months of pregnancy or shortly after childbirth. [1]

  3. Acute fatty liver of pregnancy - Wikipedia

    en.wikipedia.org/wiki/Acute_fatty_liver_of_pregnancy

    Acute fatty liver of pregnancy is a rare life-threatening complication of pregnancy that occurs in the third trimester or the immediate period after delivery. [1] It is thought to be caused by a disordered metabolism of fatty acids by mitochondria in the fetus, caused by long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency. [2]

  4. Ischemic hepatitis - Wikipedia

    en.wikipedia.org/wiki/Ischemic_hepatitis

    Ischemic hepatitis, also known as shock liver, is a condition defined as an acute liver injury caused by insufficient blood flow (and consequently insufficient oxygen delivery) to the liver. [5] The decreased blood flow ( perfusion ) to the liver is usually due to shock or low blood pressure.

  5. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.

  6. Gilbert's syndrome - Wikipedia

    en.wikipedia.org/wiki/Gilbert's_syndrome

    The enzymes that are defective in GS – UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) – are also responsible for some of the liver's ability to detoxify certain drugs. For example, Gilbert syndrome is associated with severe diarrhea and neutropenia in patients who are treated with irinotecan , which is metabolized by UGT1A1.

  7. Hepatic lipase - Wikipedia

    en.wikipedia.org/wiki/Hepatic_lipase

    The activation of HL occurs in two steps. First, HDL that makes its way to the liver, binds to HL thereby removing the heparan sulfate proteoglycan and freeing up the hepatic lipase into the bloodstream, but HL is still inactive due to the proteins on the surface of the lipoprotein. Second, HDL unbinds from HL to activate HL enzymes in the ...

  8. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    Muscle sources of the enzymes, such as intense exercise, are unrelated to liver function and can markedly increase AST and ALT. [5] Cirrhosis of the liver or fulminant liver failure secondary to hepatitis commonly reach values for both ALT and AST in the >1000 U/L range; however, many people with liver disease have normal transaminases.

  9. Acute liver failure - Wikipedia

    en.wikipedia.org/wiki/Acute_liver_failure

    Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells).