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Acrogeria (Gottron's syndrome) is a skin condition characterized by premature aging, typically in the form of unusually fragile, thin skin on the hands and feet (distal extremities). [ 1 ] This is one of the classic congenital premature aging syndromes, occurring early in life, others being pangeria ( Werner's syndrome ) and progeria ...
Pseudoxanthoma elasticum (PXE) is a genetic disease that causes mineralization of elastic fibers in some tissues. The most common problems arise in the skin and eyes, and later in blood vessels in the form of premature atherosclerosis. [2] [3] [4] PXE is caused by autosomal recessive mutations in the ABCC6 gene on the short arm of chromosome 16 ...
Solar purpura (also known as "Actinic purpura," and "Senile purpura") is a skin condition characterized by large, sharply outlined, 1- to 5-cm, dark purplish-red ecchymoses appearing on the dorsa of the forearms and less often the hands. [1] The condition is most common in elderly people of European descent.
Classical-like EDS is characterized by skin hyperextensibility with velvety skin texture and absence of atrophic scarring, generalized joint hypermobility with or without recurrent dislocations (most often shoulder and ankle), and easily bruised skin or spontaneous ecchymoses (discolorations of the skin resulting from bleeding underneath). [5]
Cutaneous asthenia is a skin disorder caused by a collagen defect. Collagen is the protein that binds the cells of the dermis together. It is also called dermatoproxy, hereditary skin fragility or cutis elastica ("elastic skin") and is found in humans, cats, dogs, [1] mink, horses, cattle and sheep.
Skin fragility syndrome (also known as "plakophilin 1 deficiency") is a cutaneous condition characterized by trauma-induced blisters and erosions. [1]