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Rabies causes about 59,000 deaths worldwide per year, [6] about 40% of which are in children under the age of 15. [16] More than 95% of human deaths from rabies occur in Africa and Asia. [1] Rabies is present in more than 150 countries and on all continents but Antarctica. [1] More than 3 billion people live in regions of the world where rabies ...
3D still showing rabies virus structure. Rhabdoviruses have helical symmetry, so their infectious particles are approximately cylindrical in shape. They are characterized by an extremely broad host spectrum ranging from plants [citation needed] to insects [citation needed] and mammals; human-infecting viruses more commonly have icosahedral symmetry and take shapes approximating regular polyhedra.
Rabies has a long history of association with dogs. The first written record of rabies is in the Codex of Eshnunna (c. 1930 BC), which dictates that the owner of a dog showing symptoms of rabies should take preventive measure against bites. If a person was bitten by a rabid dog and later died, the owner was fined heavily.
By the time symptoms develop, treatment is too late; at that stage, the virus is 100% fatal. It can take weeks or months from exposure, usually through an animal bite, to falling ill with rabies ...
Different viruses can infect all the organs and tissues of the body and the outcomes range from mild or no symptoms, to life-threatening diseases. [5] Humans cannot be infected by plant or insect viruses, but they are susceptible to infections with viruses from other vertebrates. These are called viral zoonoses or zoonotic infections. [6]
Inosine pranobex (BAN; also known as inosine acedoben dimepranol (), methisoprinol, inosiplex or Isoprinosine) is an antiviral drug that is a combination of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3.
The rabies vaccine is a vaccine used to prevent rabies. [11] There are several rabies vaccines available that are both safe and effective. [11] Vaccinations must be administered prior to rabies virus exposure or within the latent period after exposure to prevent the disease. [12]
Mokola lyssavirus, commonly called Mokola virus (MOKV), is an RNA virus related to rabies virus that has been sporadically isolated from mammals across sub-Saharan Africa. . The majority of isolates have come from domestic cats exhibiting symptoms characteristically associated to rabies virus infecti