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Menotropin preparations are designed for use in selected women where they stimulate the ovaries to mature follicles, thus making them more fertile. They are administered by typically daily injection, intramuscularly or subcutaneously, for about ten days under close supervision to adjust dose and duration of therapy.
In males over 18 years of age, reference ranges have been estimated to be 1.8–8.6 IU/L. [32] LH is measured in international units (IU). When quantifying the amount of LH in a sample in IUs, it is important to know which international standard your lot of LH was calibrated against since they can vary broadly from year to year.
In general, androgens are considered "male sex hormones", since they have masculinizing effects, while estrogens and progestogens are considered "female sex hormones" although all types are present in each sex at different levels. [6] Sex hormones include: Progestogens. Pregnenolone → Progesterone → Allopregnanedione → Allopregnanolone
Gonadotropin preparations are drugs that mimic the physiological effects of gonadotropins, used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. [1] For example, the so-called menotropins consist of LH and FSH extracted from human urine from menopausal women. [2] There are also recombinant ...
In the ovary, the FSH receptor is necessary for follicular development and expressed on the granulosa cells. [5] In the male, the FSH receptor has been identified on the Sertoli cells that are critical for spermatogenesis. [12] The FSHR is expressed during the luteal phase in the secretory endometrium of the uterus. [13]
Sex differences in human physiology are distinctions of physiological characteristics associated with either male or female humans. These differences are caused by the effects of the different sex chromosome complement in males and females, and differential exposure to gonadal sex hormones during development.
In males, Testes release sperm through the vas deferens, which is part of the reproductive system. In females, Ovaries release ova which travel through the oviducts to the uterus . So, the heterocrine nature of gonads involves their dual role in hormone secretion (endocrine) and the release of reproductive cells (exocrine), making them crucial ...
In the ovary, the LHCG receptor is necessary for follicular maturation and ovulation, as well as luteal function. Its expression requires appropriate hormonal stimulation by FSH and estradiol . The LHCGR is present on granulosa cells , theca cells, luteal cells, and interstitial cells [ 6 ] The LCGR is restimulated by increasing levels of ...
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