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In THAN, symptoms of hyperammonemia are observed within 24 hours of birth, and the causation of hyperammonemia must exclude urea cycle disorders. If the amount of ammonia entering the brain is increased, neurological disorders such as urea cycle enzyme deficiencies, Reye syndrome , seizures, and encephalopathies may occur. [ 3 ]
The Apgar score is a quick way for health professionals to evaluate the health of all newborns at 1 and 5 minutes after birth and in response to resuscitation. [1] It was originally developed in 1952 by an anesthesiologist at Columbia University, Virginia Apgar, to address the need for a standardized way to evaluate infants shortly after birth.
The blood of a two-week-old infant is collected for a Phenylketonuria, or PKU, screening. The neonatal heel prick is a blood collection procedure done on newborns. It consists of making a pinprick puncture in one heel of the newborn to collect their blood. This technique is used frequently as the main way to collect blood from neonates.
Within the first hour of life, blood glucose will typically reach its lowest point and then stabilize within 2 to 4 hours, hence breastfeeding is promoted immediately. In cases where feeding is delayed, the neonate can use lactate, free-fatty acids, and ketone bodies. Manifestations: Normal blood glucose levels range from 40 to 50 mg/dl. [1]
The Neonatal Behavioral Assessment Scale (NBAS), also known as the Brazelton Neonatal Assessment Scale (BNAS), [1] was developed in 1973 by T. Berry Brazelton and his colleagues. [2] This test purports to provide an index of a newborn's abilities, and is usually given to an infant somewhere between the age of 3 days to 4 weeks old. [ 1 ]
Neonatal sepsis of the newborn is an infection that has spread through the entire body. The inflammatory response to this systematic infection can be as serious as the infection itself. [ 26 ] In infants that weigh under 1500 g, sepsis is the most common cause of death.
Hemolytic disease of the fetus and newborn (HDN) is a condition where the passage of maternal antibodies results in the hemolysis of fetal/neonatal red cells. The antibodies can be naturally occurring such as anti-A, and anti-B, or immune antibodies developed following a sensitizing event. [ 38 ]
Neonatal sepsis is the single most common cause of neonatal death in hospital as well as community in developing country. It is difficult to clinically exclude sepsis in newborns less than 90 days old that have fever (defined as a temperature > 38 °C (100.4 °F).