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Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
In addition to their actions as reuptake inhibitors of serotonin, some SSRIs are also, coincidentally, ligands of the sigma receptors. [ 187 ] [ 188 ] Fluvoxamine is an agonist of the σ 1 receptor , while sertraline is an antagonist of the σ 1 receptor, and paroxetine does not significantly interact with the σ 1 receptor.
Sertraline is an FDA-approved medication that belongs to a class of drugs known as selective serotonin reuptake inhibitors, or SSRIs. Sertraline is approved to treat a variety of conditions ...
Selective serotonin reuptake inhibitors, ... Sertraline is the second most potent inhibitor of 5-HT re-uptake which has two very interesting characteristics that ...
Serotonin. A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT). This in turn leads to increased extracellular concentrations of serotonin and, therefore, an increase in serotonergic ...
Sertraline is a selective serotonin reuptake inhibitor prescribed to treat depression and anxiety disorders, like social anxiety disorder, panic disorder, obsessive-compulsive disorder (OCD) and ...
Selective serotonin reuptake inhibitors (SSRIs). SSRIs are modern antidepressants often used as a first-line treatment for major depressive disorder. ... Zoloft (sertraline) and Lexapro ...
Selective serotonin reuptake inhibitors include: Citalopram (Celexa, Cipramil) Escitalopram (Lexapro, Cipralex) Fluoxetine (Prozac, Sarafem) Fluvoxamine (Luvox, Faverin) Paroxetine (Paxil, Seroxat) Sertraline (Zoloft, Lustral)