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  2. Clonal selection - Wikipedia

    en.wikipedia.org/wiki/Clonal_selection

    In immunology, clonal selection theory explains the functions of cells of the immune system (lymphocytes) in response to specific antigens invading the body. The concept was introduced by Australian doctor Frank Macfarlane Burnet in 1957, in an attempt to explain the great diversity of antibodies formed during initiation of the immune response .

  3. Opinion - Silence of the labs: How a censorship campaign ...

    www.aol.com/opinion-silence-labs-censorship...

    When Sen. Tom Cotton (R-Ark) raised the theory, he was chastised for “repeat[ing] a fringe theory suggesting that the ongoing spread of a coronavirus is connected to research in the disease ...

  4. mRNA vaccine - Wikipedia

    en.wikipedia.org/wiki/MRNA_vaccine

    The COVID-19 mRNA vaccines from Moderna and Pfizer–BioNTech had short-term efficacy rates of over 90 percent against the original SARS-CoV-2 virus. Prior to mRNA, drug trials on pathogens other than COVID-19 were not effective and had to be abandoned in the early phases of trials. The reason for the efficacy of the new mRNA vaccines is not clear.

  5. Immune network theory - Wikipedia

    en.wikipedia.org/wiki/Immune_network_theory

    The theory accounts for the ability of T cells to have regulatory roles in both helping and suppressing immune responses. In 1976 Murphy et al. and Tada et al. independently reported a phenomenon in mice called I-J. [17] [18] From the perspective of the symmetrical network theory, I-J is one of the most important phenomena in immunology, while for many immunologists who are not familiar with ...

  6. David Talmage - Wikipedia

    en.wikipedia.org/wiki/David_Talmage

    He made significant contributions to the clonal selection theory. [2] Career ... Journal of Immunology. 153 (3): 919 ...

  7. Clonal anergy - Wikipedia

    en.wikipedia.org/wiki/Clonal_anergy

    This process – called "clonal expansion" – allows the body to quickly mobilise an army of clones, as and when required. Such immune response is anticipatory and its specificity is assured by pre-existing clones of lymphocytes, which expand in response to specific antigen (process called "clonal selection").

  8. Clonal selection algorithm - Wikipedia

    en.wikipedia.org/wiki/Clonal_Selection_Algorithm

    Clonal Selection Pseudo code on AISWeb; CLONALG in Matlab developed by Leandro de Castro and Fernando Von Zuben; Optimization Algorithm Toolkit in Java developed by Jason Brownlee which includes the following clonal selection algorithms: Adaptive Clonal Selection (ACS), Optimization Immune Algorithm (opt-IMMALG), Optimization Immune Algorithm (opt-IA), Clonal Selection Algorithm (CLONALG ...

  9. Cell-mediated immunity - Wikipedia

    en.wikipedia.org/wiki/Cell-mediated_immunity

    Cellular immunity protects the body through: T-cell mediated immunity or T-cell immunity: activating antigen-specific cytotoxic T cells that are able to induce apoptosis in body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;