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In vivo magnetic resonance spectroscopy (MRS) is a specialized technique associated with magnetic resonance imaging (MRI). [1] [2]Magnetic resonance spectroscopy (MRS), also known as nuclear magnetic resonance (NMR) spectroscopy, is a non-invasive, ionizing-radiation-free analytical technique that has been used to study metabolic changes in brain tumors, strokes, seizure disorders, Alzheimer's ...
Diffusion imaging is an MRI method that produces in vivo magnetic resonance images of biological tissues sensitized with the local characteristics of molecular diffusion, generally water (but other moieties can also be investigated using MR spectroscopic approaches). [15] MRI can be made sensitive to the motion of molecules.
The data generated by fMRS usually shows spectra of resonances, instead of a brain image, as with MRI. The area under peaks in the spectrum represents relative concentrations of metabolites. fMRS is based on the same principles as in vivo magnetic resonance spectroscopy (MRS). However, while conventional MRS records a single spectrum of ...
For example, in the context of oncology, an MRI scan may reveal the shape and size of a tumor, while an MRSI study provides additional information about the metabolic activity occurring in the tumor. MRSI can be performed on a standard MRI scanner, and the patient experience is the same for MRSI as for MRI.
COSMOS assumes a model-free susceptibility distribution and keeps full fidelity to the measured data. This method has been validated extensively in in vitro, ex vivo and phantom experiments. Quantitative susceptibility maps obtained from in vivo human brain imaging also showed high degree of agreement with previous knowledge about brain anatomy ...
MRI has the advantages of having very high spatial resolution and is very adept at morphological imaging and functional imaging. MRI does have several disadvantages though. First, MRI has a sensitivity of around 10 −3 mol/L to 10 −5 mol/L which, compared to other types of imaging, can be very limiting. This problem stems from the fact that ...
Resting state fMRI (rs-fMRI or R-fMRI), also referred to as task-independent fMRI or task-free fMRI, is a method of functional magnetic resonance imaging (fMRI) that is used in brain mapping to evaluate regional interactions that occur in a resting or task-negative state, when an explicit task is not being performed.
Desktopmodells of SPECT, uCT and PET for preclinical use. Preclinical imaging is the visualization of living animals for research purposes, [1] such as drug development. . Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, in animals responding to physiological or environmental c