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  2. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [11] For pain or fever, effects typically begin within 30 minutes. [11] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [11] One common adverse effect is an upset ...

  3. History of aspirin - Wikipedia

    en.wikipedia.org/wiki/History_of_aspirin

    The aspirin patent had expired, Bayer still had control over the Aspirin trademark, seen at the bottom of the ad, and a "patriotic" slogan to buy war bonds. Also shows the factory in New York State. The U.S. ASA patent expired in 1917, but Sterling owned the aspirin trademark, which was the

  4. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    In short, aspirin buffers and transports the protons, acting as a competitor to ATP synthase. When high doses of aspirin are given, aspirin may actually cause hyperthermia due to the heat released from the electron transport chain, as opposed to the antipyretic action of aspirin seen with lower doses.

  5. Copper aspirinate - Wikipedia

    en.wikipedia.org/wiki/Copper_aspirinate

    Copper aspirinate can be prepared by several methods. In one route of preparation, an excess of acetylsalicylic acid is dissolved in aqueous sodium carbonate. Sodium hydroxide is not suitable for this purpose, because it will hydrolyse acetylsalicylic acid (ASA) into salicylic acid and sodium acetate. 2 HC 9 H 7 O 4 + Na 2 CO 3 → 2 NaC 9 H 7 ...

  6. Retrosynthetic analysis - Wikipedia

    en.wikipedia.org/wiki/Retrosynthetic_analysis

    Each precursor material is examined using the same method. This procedure is repeated until simple or commercially available structures are reached. These simpler/commercially available compounds can be used to form a synthesis of the target molecule. Retrosynthetic analysis was used as early as 1917 in Robinson's Tropinone total synthesis. [1]

  7. Kolbe–Schmitt reaction - Wikipedia

    en.wikipedia.org/wiki/Kolbe–Schmitt_reaction

    The Kolbe–Schmitt reaction proceeds via the nucleophilic addition of a phenoxide, classically sodium phenoxide (NaOC 6 H 5), to carbon dioxide to give the salicylate. The final step is the reaction (protonation) of the salicylate anion with an acid to form the desired salicylic acids (ortho- and para- isomers).

  8. Trump’s rapid dismantling of USAID leaves workers around ...

    www.aol.com/news/trump-rapid-dismantling-usaid...

    The Trump administration’s rapid moves to dismantle the US Agency for International Development have left thousands of workers scrambling to figure out what comes next and scores of those posted ...

  9. Salicylic acid - Wikipedia

    en.wikipedia.org/wiki/Salicylic_acid

    Salicylic acid has long been a key starting material for making acetylsalicylic acid (ASA or aspirin). [8] ASA is prepared by the acetylation of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride. [17] ASA is the standard to which all the other non-steroidal anti-inflammatory drugs are compared. In veterinary medicine ...