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If approved for HER2 low and ultra-low breast cancers after endocrine therapy, eight out of out 10 women with metastatic breast cancer could be treated with Enhertu, AstraZeneca oncology research ...
Enhertu is the first licensed targeted treatment for patients with HER2-low breast cancer that cannot be removed surgically or that has spread to other parts of the body, also known as metastatic ...
The study compared Enhertu to standard chemo in about 500 patients with HER2-low breast cancer that had spread or could not be treated with surgery. The drug stopped the progress of cancer for ...
Trastuzumab deruxtecan is indicated for the treatment of adults with unresectable (unable to be removed with surgery) or metastatic (when cancer cells spread to other parts of the body) HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting and for adults with locally advanced or metastatic HER2-positive gastric or gastroesophageal ...
Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. [31] [28] [32] [33] It is specifically used for cancer that is HER2 receptor positive. [31]
In July 2024, National Institute for Health and Care Excellence (Nice) blocked the National Health Service (NHS) from providing Enhertu, an innovative treatment for advanced HER2-low breast cancer, due to AstraZeneca and Daiichi Sankyo not offering a low enough price. Nice's decision, the first rejection of a breast cancer treatment in six ...
Pharmaceutical company AstraZeneca said Enhertu demonstrated a 72% reduction in the risk of disease progression or death in women with HER2-positive metastatic breast cancer compared to a ...
It is licensed for the treatment of breast cancer or gastric or gastroesophageal adenocarcinoma. [2] Patritumab deruxtecan, an experimental antibody–drug conjugate to treat non-small-cell lung cancer. [3] [4] [5] Ifinatamab deruxtecan, an experimental anti-cancer treatment. [6] [7]