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Use appears to be safe during pregnancy. [9] [3] It is classified as an osmotic laxative: [4] It works by increasing the amount of water in the stool. [5] Macrogol came into use as a bowel prep in 1980 and was approved for medical use in the United States in 1999. [10] [11] [12] It is available as a generic medication and over the counter.
Sodium citrate saline is one of the most effective osmotic laxatives (secondary in action only to magnesium citrate). [8] Its laxative action is the result of osmotic imbalance that extracts bound water from stool and pulls it back into the large bowel. The increased water content softens the stool and stimulates the bowel to contract (move its ...
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
Glycerin suppositories used as laxatives. Laxatives, purgatives, or aperients are substances that loosen stools [1] and increase bowel movements. They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have.
Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. [3] [4] It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. [3] It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. [1] [2]
Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. [1] [5] The medication is taken by mouth or via the rectum. [1] [6] It typically begins working in around 30 minutes when given by rectum and within twelve hours when given by mouth. [3]