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Hypotaurine is a sulfinic acid that is an intermediate in the biosynthesis of taurine. Like taurine, it also acts as an endogenous neurotransmitter via action on the glycine receptors. [1] It is an osmolyte with antioxidant properties. [2] Hypotaurine is derived from cysteine (and homocysteine). In mammals, the biosynthesis of hypotaurine from ...
Taurine is synthesized naturally in the human liver from methionine and cysteine. [5] Taurine is commonly sold as a dietary supplement, but there is no good clinical evidence that taurine supplements provide any benefit to human health. [6] Taurine is used as a food additive for cats (who require it as an essential nutrient), dogs, and poultry. [7]
The Escherichia coli tauD gene is required for the utilization of taurine (2-aminoethanesulfonic acid) as a sulfur source and is expressed only under conditions of sulfate starvation. TauD is an alpha-ketoglutarate-dependent dioxygenase catalyzing the oxygenolytic release of sulfite from taurine. [ 1 ]
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GitHub (/ ˈ ɡ ɪ t h ʌ b /) is a proprietary developer platform that allows developers to create, store, manage, and share their code. It uses Git to provide distributed version control and GitHub itself provides access control, bug tracking, software feature requests, task management, continuous integration, and wikis for every project. [8]
In the decomposition of taurine, it has been shown that molecular oxygen is activated by Iron II, which lies in the coordinating complex of taurine dioxygenase. [2] Here the enzyme with conjunction of an Iron II and 2-oxoglutarate maintain non-covalent bonds by electrostatic interactions, and coordinate a nucleophilic attack from dioxygen on 2-oxoglutarate carbon number 2. [3]
Metalink is an extensible metadata file format that describes one or more computer files available for download.It specifies files appropriate for a user's language and operating system; facilitates file verification and recovery from data corruption; and lists alternate download sources (mirror URIs).
In enzymology, a taurine dehydrogenase (EC 1.4.99.2) is an enzyme that catalyzes the chemical reaction.. taurine + H 2 O + acceptor sulfoacetaldehyde + NH 3 + reduced acceptor. The 3 substrates of this enzyme are taurine, H 2 O, and acceptor, whereas its 3 products are sulfoacetaldehyde, NH 3, and reduced acceptor.