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In medicine, photopheresis (aka extracorporeal photopheresis or ECP) [1] is a form of apheresis and photodynamic therapy in which blood is subject to apheresis to separate buffy coat (WBC + platelets) from whole blood, chemically treated with 8-methoxypsoralen (instilled into a collection bag or given per os in advance), exposed to ultraviolet light (UVA), and then returned to the patient. [2]
The main advantage is a single venipuncture site. It does require a larger extracorporeal volume, and takes significantly longer to perform the procedure via IFC. As such, it is less likely to be used for therapeutic reasons, and is often seen in Donation Center settings. [6]
The applications of photophoresis expand into the various divisions of science, thus physics, chemistry as well as in biology. Photophoresis is applied in particle trapping and levitation, [3] in the field flow fractionation of particles, [4] in the determination of thermal conductivity and temperature of microscopic grains [5] and also in the transport of soot particles in the atmosphere. [6]
Extracorporeal photopheresis, a therapy in which blood is treated with a photosensitizing agent and subsequently irradiated with light; External counterpulsation, a non-invasive therapy used to treat chronic angina and other ischemic heart diseases; Eye Care Professional, an individual who provides a service related to the eyes or vision
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