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Tacrolimus 0.1% Ointment As an ointment , tacrolimus is used in the treatment of dermatitis (eczema), in particular atopic dermatitis , if topical corticosteroids and moisturisers fail in helping. [ 17 ] [ 18 ] It suppresses inflammation in a similar way to steroids , and is equally as effective as a mid-potency steroid.
Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, [13] to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions.
Tacrolimus 0.1%. Topical immunosuppressants like pimecrolimus and tacrolimus may be better in the short term and appear equal to steroids after a year of use. [66] Their use is reasonable in those who do not respond to or are not tolerant of steroids. [67] [68] Treatments are typically recommended for short or fixed periods of time rather than ...
Common side effects include allergic reactions, nausea, diarrhea, headache, trouble sleeping, and feeling tired. [1] It is not recommended in people with liver failure or porphyria. [1] Use during or in the months before pregnancy may result in harm to the baby. [1] [2] Griseofulvin works by interfering with fungal mitosis. [1]
Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects. Contrary to ciclosporin and tacrolimus, drugs that affect the first phase of T lymphocyte activation, sirolimus affects the second phase, namely signal transduction and lymphocyte clonal proliferation.
Pimecrolimus has a similar mode of action to that of tacrolimus but is more selective, with no effect on dendritic (Langerhans) cells. [19] It has lower permeation through the skin than topical steroids or topical tacrolimus [20] although they have not been compared with each other for their permeation ability through mucosa. In addition, in ...
With me, Protopic works as well as steroids but without the skin thinning and other side effects that these steroids have. At the moment, I am willing to live with the risk of applying Protopic, as it really does help me at least. --Thilo 02:56, 10 September 2007 (UTC) Tacrolimus is not intended for prolonged use on large areas of the body.
Creams based on calcineurin inhibitors (tacrolimus or pimecrolimus) may also be used to control flares if other measures are not effective. [2] [8] Certain antihistamine pills might help with itchiness. [3] Things that commonly make it worse include house dust mite, stress and seasonal factors. [9] Phototherapy may be useful in some people. [2]
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