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A meningococcal polysaccharide vaccine (MPSV4) has been available since the 1970s and is the only meningococcal vaccine licensed for people older than 55. MPSV4 may be used in people 2–55 years old if the MCV4 vaccines are not available or contraindicated. Two meningococcal conjugate vaccines (MCV4) are licensed for use in the U.S. The first ...
Meningococcal meningitis is a form of bacterial meningitis. Meningitis is a disease caused by inflammation and irritation of the meninges , the membranes surrounding the brain and spinal cord. In meningococcal meningitis this is caused by the bacteria invading the cerebrospinal fluid and circulating through the central nervous system .
Meningitis caused by H. influenzae and meningococci has a better prognosis than cases caused by group B streptococci, coliforms and S. pneumoniae. [2] In adults, too, meningococcal meningitis has a lower mortality (3–7%) than pneumococcal disease. [3]
Acute meningococcal meningitis can lead to an exudate within the leptomeninges along the surface of the brain. [12] Because the arachnoid is connected to the pia by cob-web like strands, it is structurally continuous with the pia, hence the name pia-arachnoid or leptomeninges.
The strain of meningococcal disease currently circulating in Virginia is also spreading more widely across the US right now
Matthew C. Washam, medical director of Epidemiology at Nationwide Children's Hospital says " meningitis is an infection that causes the protective membrane (meninges) of the brain and spinal cord ...
Neisseria meningitidis causes meningococcal meningitis and sepsis. Opc (formerly called 5C) is one of the major outer membrane proteins and has been shown to play an important role in meningococcal adhesion and invasion of epithelial and endothelial cells, mediating attachment to host cells by binding proteoglycan cell-surface receptors. [1]
This invasive meningococcal disease has been dangerously prevalent in recent months after an historic surge last year. As of March 25, the CDC says at least 143 known cases were reported in the ...
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