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Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [ 1 ] [ 2 ] [ 3 ] It is either taken by mouth or applied to the skin as a cream or ointment.
In fact, when it comes to toenail fungus, oral prescription terbinafine is considered the most effective treatment. That said, the terbinafine in topical antifungals doesn't have the same effect ...
Ketoconazole by mouth is not recommended due to side effects. [27] Oral terbinafine is better tolerated than itraconazole. [28] For superficial white onychomycosis, systemic rather than topical antifungal therapy is advised. [29] Topical agents include ciclopirox nail paint, amorolfine, and efinaconazole.
Before oral antifungal therapies are used to treat nail disease, a confirmation of the fungal infection should be made. [36] Approximately half of suspected cases of fungal infection in nails have a non-fungal cause. [36] The side effects of oral treatment are significant and people without an infection should not take these drugs. [36]
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Topical antifungal medications usually come with side effects. Some patients may develop itching or local irritations after the application of these products. Consult a pharmacist or clinician if the treated area shows signs of increased irritation or possible sensitization such as erythema , pruritus , burning, blistering , swelling , or oozing.