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  2. Coronary Heart Disease - Treatment - NHLBI, NIH

    www.nhlbi.nih.gov/health/coronary-heart-disease/treatment

    Last updated on December 20, 2023. Coronary heart disease treatment can include heart-healthy lifestyle changes. It can also include medicines or procedures to help manage high blood pressure, high cholesterol levels, or other conditions that may worsen your heart disease.

  3. Coronary Heart Disease Research - NHLBI, NIH

    www.nhlbi.nih.gov/research/coronary-heart-disease

    For almost 75 years, the NHLBI has been at the forefront of improving the nation’s health and reducing the burden of heart and vascular diseases. Heart disease, including coronary heart disease, remains the leading cause of death in the United States. However, the rate of heart disease deaths has declined by 70% over the past 50 years, thanks ...

  4. Sickle Cell Disease - Treatment - NHLBI, NIH

    www.nhlbi.nih.gov/health/sickle-cell-disease/treatment

    View fact sheet. Crizanlizumab-tmca is approved for adults and children ages 16 years and older who have sickle cell disease. The medicine is given through an intravenous (IV) line in the vein once a month. The medicine helps prevent blood cells from sticking to blood vessel walls and blocking blood flow.

  5. Cure Sickle Cell Initiative - NHLBI, NIH

    www.nhlbi.nih.gov/science/cure-sickle-cell-initiative

    The Cure Sickle Cell Initiative is an NHLBI-led collaborative research effort that is accelerating the development of gene therapies to cure sickle cell disease. The Initiative identifies and supports promising gene therapies that are currently being tested in multicenter clinical research trials. One of these studies is co-funded by the ...

  6. Cardiovascular disease is on the rise, but we know how to curb...

    www.nhlbi.nih.gov/news/2021/cardiovascular-disease-rise-we-know-how-curb-it...

    The trend indicates that cases of cardiovascular disease are likely to increase substantially as a result of population growth and aging, according to the researchers. “More people means more heart attacks, strokes, and heart failure hospitalizations,” Roth said. On the other hand, “aging is a very complex phenomenon,” he added.

  7. Physical Activity and Your Heart - Benefits | NHLBI, NIH

    www.nhlbi.nih.gov/health/heart/physical-activity/benefits

    When done regularly, moderate- and vigorous-intensity physical activity strengthens your heart muscle. This improves your heart's ability to pump blood to your lungs and throughout your body. As a result, more blood flows to your muscles, and oxygen levels in your blood rise. Capillaries, your body's tiny blood vessels, also widen.

  8. Anti-inflammatory diets may reduce the risk of cardiovascular...

    www.nhlbi.nih.gov/news/2020/anti-inflammatory-diets-may-reduce-risk...

    Physicians use these tests to help identify patients at risk for heart and vascular disease. Elevated cholesterol, for example, is a risk factor for atherosclerosis, the accumulation of plaque in the arteries that can limit blood flow and lead to a heart attack, stroke, or chronic kidney disease. To assess how diet-related inflammation ...

  9. Heart Failure - Treatment - NHLBI, NIH

    www.nhlbi.nih.gov/health/heart-failure/treatment

    Right-sided heart failure. If you have right-sided heart failure, your doctor may prescribe two types of medicines. Medicines that remove extra sodium and fluid from your body, including diuretics and aldosterone antagonists (such as spironolactone) lower the amount of blood that the heart must pump. Very high doses of diuretics may cause low ...

  10. Heart Failure - What Is Heart Failure? - NHLBI, NIH

    www.nhlbi.nih.gov/health/heart-failure

    More than 6 million adults in the United States have heart failure, according to the Centers for Disease Control and Prevention. Children can also have heart failure, but this health topic focuses on heart failure in adults. Heart failure can develop suddenly (the acute kind) or over time as your heart gets weaker (the chronic kind).

  11. Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH

    www.nhlbi.nih.gov/health/sickle-cell-disease

    Sickle cell disease is an inherited blood disorder that affects hemoglobin, the protein that carries oxygen through the body. Misshapen red blood cells can block blood flow causing lifelong health problems. The only cure is a blood and bone marrow transplant, but treatments are available to manage the condition.