Search results
Results From The WOW.Com Content Network
Pernicious anemia is the most common cause of clinically evident vitamin B 12 deficiency worldwide. [14] Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [8] It more commonly affects people of northern European descent. [2]
Pernicious number. In number theory, a pernicious number is a positive integer such that the Hamming weight of its binary representation is prime, that is, there is a prime number of 1s when it is written as a binary number. [1]
Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [2] [8] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
Pernicious is a Thai-American supernatural horror film directed by James Cullen Bressack, [1] who also wrote the story along with co-writer Taryn Hillin. [2] The film stars Ciara Hanna , Emily O'Brien , and Jackie Moore.
Pernicious anemia [31] is a form of megaloblastic anemia due to vitamin B 12 deficiency dependent on impaired absorption of vitamin B 12. Lack of dietary B 12 causes non-pernicious megaloblastic anemia. Anemia of folate deficiency, [31] as with vitamin B 12, causes megaloblastic anemia
Megaloblastic anemia is a type of macrocytic anemia. An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage.
The presence of hypersegmented neutrophils is an important diagnostic feature of megaloblastic anaemias. Hypersegmentation can also be seen in many other conditions but with relatively less diagnostic significance. Hypersegmentation can sometimes be difficult to assert since interobserver variation is high and segmentation may vary with race.