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Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [9] It can be taken by mouth or by injection into a vein. [1][10] It is also available in the fixed-dose combination medication omeprazole/sodium bicarbonate as Zegerid [11][12] and as Konvomep. [13]
Proton-pump inhibitor. Proton-pump inhibitors (PPIs) are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H + /K + ATPase proton pump. [1] Proton-pump inhibitors have largely superseded the H 2 -receptor antagonists, a group of medications with ...
Anti-ulcer agents are medications or supplements used to cure the damage of mucosal layer on organs to prevent the damage from further extending to deeper regions to cause complications. An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12.
A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [11] [12] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [6]
Proton-pump inhibitors (PPIs), such as omeprazole, are the most effective, followed by H 2 receptor blockers, such as ranitidine. [43] If a once-daily PPI is only partially effective they may be used twice a day. [43] They should be taken one half to one hour before a meal. [42] There is no significant difference between PPIs. [42]
Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome. [ 5 ...