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The potential efficacy of probiotics to treat AAD depends on the probiotic strains and dosage. [100] [101] One review recommended for children L. rhamnosus or Saccharomyces boulardii at 5 to 40 billion colony-forming units/day, given the modest number needed to treat and the likelihood that adverse events are very rare. [94]
Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen peels in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic , metabolic, and genetic properties, [ 1 ] S. boulardii is a grouping of S. cerevisiae strains, all sharing a >99% genomic relatedness.
Henri Boulard was a French microbiologist who discovered the yeast Saccharomyces boulardii in 1923. He noticed people chewing on the skins of lychees and mangosteens to treat diarrhea during a cholera epidemic. He isolated and identified this strain of yeast, a probiotic. [1]
Auto-brewery syndrome (ABS) (also known as gut fermentation syndrome, endogenous ethanol fermentation or drunkenness disease) is a condition characterized by the fermentation of ingested carbohydrates in the gastrointestinal tract of the body caused by bacteria or fungi. [1]
Conversely, Lactobacillus fermentum and Saccharomyces boulardii have been found to be ineffective. [4] [failed verification] A combination of Lactobacillus plantarum and Lactobacillus rhamnosus has been found to be effective in suppressing bacterial overgrowth of abnormal gas producing organisms in the small intestine. [32] [non-primary source ...
[76] [81] Saccharomyces boulardii causes about 40% cases of invasive Saccharomyces infections [81] and is more likely (in comparison to other S. cerevisiae strains) to cause invasive infection in humans without general problems with immunity, [81] though such adverse effect is very rare relative to Saccharomyces boulardii therapeutic ...