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Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen peels in 1923 by French scientist Henri Boulard. Although early reports claimed distinct taxonomic , metabolic, and genetic properties, [ 1 ] S. boulardii is a grouping of S. cerevisiae strains, all sharing a >99% genomic relatedness.
Henri Boulard was a French microbiologist who discovered the yeast Saccharomyces boulardii in 1923. He noticed people chewing on the skins of lychees and mangosteens to treat diarrhea during a cholera epidemic. He isolated and identified this strain of yeast, a probiotic. [1]
Racecadotril, also known as acetorphan, is an antidiarrheal medication which acts as a peripheral enkephalinase inhibitor. [3] Unlike other opioid medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect — it reduces the secretion of water and electrolytes into the intestine. [3]
The strain Saccharomyces cerevisiae var. boulardii is industrially manufactured and used clinically as a medication. Several clinical and experimental studies have shown that S. cerevisiae var. boulardii is, to lesser or greater extent, useful for prevention or treatment of several gastrointestinal diseases. [71]
Conversely, Lactobacillus fermentum and Saccharomyces boulardii have been found to be ineffective. [4] [failed verification] A combination of Lactobacillus plantarum and Lactobacillus rhamnosus has been found to be effective in suppressing bacterial overgrowth of abnormal gas producing organisms in the small intestine. [32] [non-primary source ...
Saccharomyces is a genus of fungi that includes many species of yeasts. Saccharomyces is from Greek σάκχαρον (sugar) and μύκης (fungus) and means sugar fungus . Many members of this genus are considered very important in food production where they are known as brewer's yeast, baker's yeast and sourdough starter among others.