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[11] [12] At least three independent methods have successfully converted CBD to THC. Despite the CBD and THC having the same molecular weight, multiple analytical methods are able to differentiate them. [11] "on the recovery of both THC (86.7−90.0%) and CBD (92.3−95.6%). The slightly lower recovery of THC can be explained by the fact that ...
A 2021 review found little effect of using non-inhaled cannabis to relieve chronic pain. [8] According to a 2019 systematic review, there have been inconsistent results of using cannabis for neuropathic pain, spasms associated with multiple sclerosis and pain from rheumatic disorders, but
[4] [19] CBD does not have the same psychoactivity as THC, [24] [25] and can modulate the psychoactive effects of THC on the body if both are present. [16] [24] [26] [27] Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C, potentially leading to its partial transformation into THC. [28]
[1] [2] THC and CBD are stored mostly in the trichomes of the plant, [3] and can cause psychological and physical impairment in the user, via the endocannabinoid system and unique receptors. [ 4 ] [ 5 ] THC increases dopamine levels in the brain, which attributes to the euphoric and relaxed feelings cannabis provides.
Oral cannabis extract and THC both were rated as possibly effective for improving objective measures of spasticity. [74] [75] Centrally mediated pain and painful spasms. Based on the results of 4 high quality trials and 4 low quality trials, oral cannabis extract was rated as effective, and THC as probably effective in treating central pain and ...
Cannabis contains over 100 different cannabinoid compounds, many of which have displayed psychoactive effects. The most distinguished cannabinoids are tetrahydrocannabinol (THC) and cannabidiol (CBD), with THC being the primary psychoactive agent. [24] [12] The effects of THC and CBD are salient regarding psychosis and anxiety. [25]
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CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]