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Transfusion-dependent anemia is a form of anemia characterized by the need for continuous blood transfusion. It is a condition that results from various diseases, and is associated with decreased survival rates. [1][2] Regular transfusion is required to reduce the symptoms of anemia by increasing functional red blood cells and hemoglobin count.
Transfusion dependent anemia is a form of anemia where ongoing blood transfusion are required. [87] Most people with myelodysplastic syndrome develop this state at some point in time. [88] Beta thalassemia may also result in transfusion dependence. [89] [90] Concerns from repeated blood transfusions include iron overload. [88]
Blood transfusion is the process of transferring blood products into a person's circulation intravenously. [1] Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, plasma ...
An exchange transfusion is a blood transfusion in which the patient 's blood or components of it are exchanged with (replaced by) other blood or blood products. [1] The patient's blood is removed and replaced by donated blood or blood components. This exchange transfusion can be performed manually or using a machine (apheresis).
In transfusion medicine, transfusion-associated circulatory overload (aka TACO) is a transfusion reaction (an adverse effect of blood transfusion) resulting in signs or symptoms of excess fluid in the circulatory system (hypervolemia) within 12 hours after transfusion. [2] The symptoms of TACO can include shortness of breath (dyspnea), low ...
TA-GvHD. Specialty. Hematology. Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of blood transfusion, in which the immunologically competent donor T lymphocytes mount an immune response against the recipient's lymphoid tissue. [1] These donor lymphocytes engraft, recognize recipient cells as foreign and mount ...
Long-term transfusion therapy (in those with transfusion dependent beta thalassemia) is a treatment used to maintain hemoglobin levels at a target pre-transfusion hemoglobin level of 9–10.5 g/dL (11–12 g/dL in those with concomitant heart disease). [8] To ensure quality blood transfusions, the packed red blood cells should be leucoreduced.
Hematology. Febrile non-hemolytic transfusion reaction (FNHTR) is the most common type of transfusion reaction. It is a benign occurrence with symptoms that include fever but not directly related with hemolysis. [1] It is caused by cytokine release from leukocytes within the donor product as a consequence of white blood cell breakdown [2] [3][4 ...