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Leqembi is a medication that clears highly-toxic protofibrils, a type of protein, from the body. A medication designed to slow early Alzheimer’s disease (AD) may soon have a new dosing schedule.
Leqembi, known generically as lecanemab, is a monoclonal antibody that works to remove a protein called amyloid from the brain. It received full Food and Drug Administration approval in July.
Lecanemab, sold under the brand name Leqembi, is a monoclonal antibody medication used for the treatment of Alzheimer's disease. [ 2 ] [ 4 ] Lecanemab is an amyloid beta -directed antibody. [ 2 ] It is given via intravenous infusion to patients with mild cognitive impairment or mild dementia. [ 2 ]
The drug's prescribing information will carry the most serious type of warning, indicating that Leqembi can cause brain swelling and bleeding, side effects that can be dangerous in rare cases.
Leqembi, co-developed by Biogen and its Japanese partner Eisai, had won standard approval from the U.S. Food and Drug Administration last July. It sees a potential rival in Eli Lilly's ...
Lecanemab, sold under the brand name Leqembi, is a monoclonal antibody medication used for the treatment of Alzheimer's disease. [ 23 ] [ 24 ] Lecanemab is an amyloid beta -directed antibody. [ 23 ] It is given via intravenous infusion to patients with mild cognitive impairment or mild dementia. [ 23 ]
Each antibody binds only one specific antigen. Monoclonal antibodies (mAbs) have varied therapeutic uses. It is possible to create a mAb that binds specifically to almost any extracellular target, such as cell surface proteins and cytokines.
Makers of the new Alzheimer's drug, Leqembi, say their twice-monthly infusion could be available in injection form at pharmacies by early 2025 — if all goes well in ongoing trials and the ...
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