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Fibrocartilage is a tough, dense, and fibrous material that helps fill in the torn part of the cartilage; however, it is not an ideal replacement for the smooth, glassy articular cartilage that normally covers the surface of joints.
Cartilage growth thus refers to the matrix deposition, but can also refer to both the growth and remodeling of the extracellular matrix. Due to the great stress on the patellofemoral joint during resisted knee extension, the articular cartilage of the patella is among the thickest in the human body.
Elastic cartilage, fibroelastic cartilage or yellow fibrocartilage [1] is a type of cartilage present in the pinnae (auricles) of the ear giving it shape, [2] provides shape for the lateral region of the external auditory meatus, [3] medial part of the auditory canal [3] Eustachian tube, corniculate and cuneiform laryneal cartilages, [3] and the epiglottis.
This technique is known as AMIC (Autologous Matrix-Induced Chondrogenesis) and was first published in 2003. [ 1 ] Microfracture techniques show new potential, as animal studies indicate that microfracture-activated skeletal stem-cells form articular cartilage , instead of fibrous tissue, when co-delivered with a combination of BMP2 and VEGF ...
They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. Although the word chondroblast is commonly used to describe an immature chondrocyte, the term is imprecise, since the progenitor of chondrocytes (which are mesenchymal stem cells) can differentiate into various cell types, including osteoblasts.
The perichondrium (from Greek περί, peri, 'around' and χόνδρος, chondros, 'cartilage') is a layer of dense irregular connective tissue that surrounds the cartilage of developing bone.
The extracellular matrix secreted by chondroblasts is composed of fibers, collagen, hyaluronic acid, proteoglycans, glycoproteins, water, and a host of macromolecules. Within finished cartilage, collagen fibers compose 10-20% of the volume, water 65-80%, and the proteoglycan-hyaluronic acid aggregates the remaining portion.
Isogenous groups differentiate into individual chondrocytes where they continue to produce and deposit extracellular matrix (ECM), lengthening the cartilage and increasing its diameter. [3] [5] This is termed interstitial growth and is one of only two ways cartilage can grow. [4] Cartoon representation of hyaline cartilage with isogenous groups.