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They are key to an experimental autologous cell therapy (Contego) for metastatic melanoma. [15] Autologous TIL therapy for metastatic melanoma has broad T cell recognition of both defined and undefined tumor antigens against all human leukocyte antigen (HLA) restrictions.
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...
Lymphocyte homing receptors are cell adhesion molecules [1] expressed on lymphocyte cell membranes that recognize addressins on target tissues. Lymphocyte homing refers to adhesion of the circulating lymphocytes in blood to specialized endothelial cells within lymphoid organs. [2]
Self-retraction is a request from an author and/or co-authors to retract its own work from being published. Self-retraction by an author is recommended because once it gets retracted from the journal, then it can affect the author(s) because investigations can begin which will have an effect the author's reputation.