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Due to the risks of certain side effects of the drug, including abuse and misuse, a person must administer the nasal spray in a clinic or doctor’s office under medical supervision. Alternative ...
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
Ketamine potentiates the sedative effects of propofol [86] and midazolam. [87] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [88] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
Lighter Side. Politics. Science & Tech. Sports. Weather. ... the ketamine-derived nasal spray sold under the brand name Spravato (esketamine), is indicated for patients with treatment-resistant ...
Treatment-resistant depression: Esketamine, which is made from ketamine, has FDA approval in nasal spray form to help patients with treatment-resistant depression — referring to people who have ...
Since 2010, ketamine has been prescribed off-label to patients with severe depression with the informed consent of patients. [26] In 2019, the FDA approved the use of esketamine (Spravato) as a nasal spray, in conjunction with an oral antidepressant, for treatment-resistant depression in adults.
The U.S. Food and Drug Administration expanded approval for Johnson & Johnson’s nasal spray, ... Lighter Side. Politics. Science & Tech ... The ketamine-derived drug was first approved in 2019 ...
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
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