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Acute decompensated heart failure (ADHF) is a sudden worsening of the signs and symptoms of heart failure, which typically includes difficulty breathing , leg or feet swelling, and fatigue. [1] ADHF is a common and potentially serious cause of acute respiratory distress .
Heart failure may also be classified as acute or chronic. Chronic heart failure is a long-term condition, usually kept stable by the treatment of symptoms. Acute decompensated heart failure is a worsening of chronic heart failure symptoms, which can result in acute respiratory distress. [66]
CXL 1020 is an experimental drug that is being investigated as a treatment for acute decompensated heart failure.CXL 1020 functions as a nitroxyl donor; nitroxyl is the reduced, protonated version of nitric oxide. [1]
Short-term treatment of cardiac decompensation can be achieved through administration of dobutamine, resulting in an increase in heart contractility via an inotropic effect. [ 1 ] Kidney failure can also occur following a slow degradation of kidney function due to an underlying untreated illness; the symptoms of the latter can then become much ...
Indapamide is a thiazide-like diuretic [4] drug used in the treatment of hypertension, as well as decompensated heart failure.Combination preparations with perindopril (an ACE inhibitor antihypertensive) are available.
Alcoholic cardiomyopathy (ACM) is a disease in which the long-term consumption of alcohol leads to heart failure. [1] ACM is a type of dilated cardiomyopathy. The heart is unable to pump blood efficiently, leading to heart failure. It can affect other parts of the body if the heart failure is severe.
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