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Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
The birth defects caused by thalidomide led to the development of greater drug regulation and monitoring in many countries. [9] [11] It was approved in the United States in 1998 for use as a treatment for cancer. [6] It is on the World Health Organization's List of Essential Medicines. [12] It is available as a generic medication. [8] [13]
rhesus rotavirus vaccine-tetravalent (RotaShield) 1999 US Withdrawn due to risk of intussusception. [47] Rimonabant (Acomplia) 2008 Worldwide Risk of severe depression and suicide. [14] Rofecoxib 2004 Worldwide Withdrawn by Merck & Co. Risk of myocardial infarction and stroke. [2] Rosiglitazone (Avandia) 2010 Europe Risk of heart attacks and death.
Early in the pandemic, he said, research moved quickly, with researchers desperate to better understand the SARS-CoV-2 virus that causes COVID-19, and find effective treatments for very sick people.
GI problems are also common among kids with Long COVID. Stomach pain, nausea, and vomiting are telltale signs of the condition among children younger than 12, according to 2024 research published ...
Phocomelia is a congenital condition that involves malformations of human arms and legs which result in a flipper-like appendage. [1] [2] A prominent cause of phocomelia is the mother being prescribed the use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined.
The most common findings are lower limb fusion into a single extremity, deformities of the sacrum and pelvic girdle, absence of external genitalia, absence of anal patency, and lethal renal ...
Some claimed vaccine injuries are not, in fact, caused by vaccines; for example, there is a subculture of advocates who attribute their children's autism to vaccine injury, [7] despite the fact that vaccines do not cause autism. [8] [9] Claims of vaccine injuries appeared in litigation in the United States in the latter part of the 20th century.