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View/Edit Mouse Phosphate carrier protein, mitochondrial is a protein that in humans is encoded by the SLC25A3 gene . [ 5 ] [ 6 ] The encoded protein is a transmembrane protein located in the mitochondrial inner membrane and catalyzes the transport of phosphate ions across it for the purpose of oxidative phosphorylation .
[39] [40] Furthermore, there is fairly rapid turnover of mitochondria, so that a mitochondrion with MT-COI-mutated chromosomes and a positive selection bias could shortly become the major type of mitochondrion in a cell. The average half-life of mitochondria in rats, depending on cell type, is between 9 and 24 days, [41] and in mice is about 2 ...
A mitochondrion (pl. mitochondria) is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi.Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. [2]
Mitochondrial DNA is the small circular chromosome found inside mitochondria. These organelles, found in all eukaryotic cells, are the powerhouse of the cell. [1] The mitochondria, and thus mitochondrial DNA, are passed exclusively from mother to offspring through the egg cell.
The mitochondrial unfolded protein response (UPR mt) is a cellular stress response related to the mitochondria. The UPR mt results from unfolded or misfolded proteins in mitochondria beyond the capacity of chaperone proteins to handle them. [1] The UPR mt can occur either in the mitochondrial matrix or in the mitochondrial inner membrane. [1]
Mitochondria are dynamic organelles with the ability to fuse and divide , forming constantly changing tubular networks in most eukaryotic cells. These mitochondrial dynamics, first observed over a hundred years ago [ 1 ] are important for the health of the cell, and defects in dynamics lead to genetic disorders .
Mitochondria are organelles surrounded by membranes, distributed in the cytosol of most eukaryotic cells. Its main function is the conversion of potential energy of pyruvate molecules into ATP. Português: o diagrama mostra uma secção de uma mitocôndria de célula eucariótica.
MT-ND1 is located in mitochondrial DNA from base pair 3,307 to 4,262. [5] The MT-ND1 gene produces a 36 kDa protein composed of 318 amino acids. [10] [11] MT-ND1 is one of seven mitochondrial genes encoding subunits of the enzyme NADH dehydrogenase (ubiquinone), together with MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, and MT-ND6.