Search results
Results From The WOW.Com Content Network
blast.ncbi.nlm.nih.gov /Blast.cgi In bioinformatics , BLAST ( basic local alignment search tool ) [ 3 ] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.
The NCBI assigns a unique identifier (taxonomy ID number) to each species of organism. [5] The NCBI has software tools that are available through web browsers or by FTP. For example, BLAST is a sequence similarity searching program. BLAST can do sequence comparisons against the GenBank DNA database in less than 15 seconds.
Highly parallel Scalable BLAST: Both: Oehmen et al. [14] 2011 Sequilab Linking and profiling sequence alignment data from NCBI-BLAST results with major sequence analysis servers/services: Nucleotide, peptide: 2010 SAM Local and global search with profile Hidden Markov models, more sensitive than PSI-BLAST: Both: Karplus K, Krogh A [15] 1999 SSEARCH
A BLAST variant called MegaBLAST indexes 4 databases to speed up alignments. [ 9 ] BLAT can extend on multiple perfect and near-perfect matches (default is 2 perfect matches of length 11 for nucleotide searches and 3 perfect matches of length 4 for protein searches), while BLAST extends only when one or two matches occur close together.
NCBI-BLAST, an algorithm for comparing biological sequences from the NCBI; Ensembl, automatic gene annotation by the EMBL-EBI and Sanger Institute; FlyBase is a database of model organism Drosophila melanogaster; GoPubMed is a knowledge-based search engine for biomedical texts; iHOP, information hyperlinked over proteins via gene/protein synonyms
In 1991, Entrez was introduced in CD form. In 1993, a client-server version of the software provided connectivity with the internet. In 1994, NCBI established a website, and Entrez was a part of this initial release. In 2001, Entrez bookshelf was released and in 2003, the Entrez Gene database was developed. [6]
Eugene Wimberly "Gene" Myers, Jr. (born December 31, 1953) is an American computer scientist and bioinformatician, who is best known for contributing to the early development of the NCBI's BLAST tool for sequence analysis.
[4] [5] NCBI is the home of GenBank, [6] the U.S. node of the International Sequence Database Consortium, and PubMed, one of the most heavily used sites in the world for the search and retrieval of biomedical information. Lipman is one of the original authors of the BLAST sequence alignment program, and a respected figure in bioinformatics.