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The three main active ingredients in Neosporin are neomycin sulfate, polymyxin B sulfate, and bacitracin zinc. [20] [7] One of the main components is neomycin sulfate, which is a type of antibiotic discovered in 1949 by microbiologist Selman Waksman at Rutgers University. [21]
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As bacitracin zinc salt, in combination with other topical antibiotics (usually polymyxin B and neomycin) as an ointment ("triple antibiotic ointment," with the brand name Neosporin), it is used for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections. A non-ointment form of ...
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Its use is thus restricted to the oral treatment of intestinal infections. [21] Neomycin B is composed of four linked moieties: D-neosamine, 2-deoxystreptamine (2-DOS), D-ribose, and L-neosamine. [citation needed] Neomycin A, also called neamine, contains D-neosamine and 2-deoxystreptamine.
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