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Taking metformin with food can reduce the risk of gastrointestinal side effects, so try taking it with the same meal each day. If you take one metformin tablet a day, it’s usually recommended ...
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [ 76 ] [ 81 ] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
Diarrhea. Flatulence. Asthenia (feeling weak or lacking energy) Stomach pain. Headache. Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication ...
Diarrhea is a well-known side effect of metformin. Learn more about why this gut-related side effect happens and how to manage it. Does Metformin Cause Diarrhea?
In the developed world, and increasingly elsewhere, type 2 diabetes is the largest cause of nontraumatic blindness and kidney failure. [27] It has also been associated with an increased risk of cognitive dysfunction and dementia through disease processes such as Alzheimer's disease and vascular dementia . [ 28 ]
Vildagliptin/metformin is indicated in the treatment of type-2 diabetes mellitus: [4] [6] [7] it is indicated in the treatment of adults who are unable to achieve sufficient glycaemic control at their maximally tolerated dose of oral metformin alone or who are already treated with the combination of vildagliptin and metformin as separate tablets.
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...