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Macrocytic anemia is a class of anemia characterized by the presence of predominantly larger-than-normal red blood cells (RBC, also known as erythrocytes) accompanied by low numbers of RBC and often also with insufficient hemoglobin content per cell. Macrocytic anemia occurs when – despite the larger cell size – such factors result in ...
Macrocytosis is a condition where red blood cells are larger than normal. [1] These enlarged cells, also known as macrocytes, are defined by a mean corpuscular volume (MCV) that exceeds the upper reference range established by the laboratory and hematology analyzer (usually >110 fL). [ 2 ]
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Postprandial somnolence (colloquially known as food coma, after-dinner dip, or "the itis") is a normal state of drowsiness or lassitude following a meal. Postprandial somnolence has two components: a general state of low energy related to activation of the parasympathetic nervous system in response to mass in the gastrointestinal tract , and a ...
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This leads to continuing cell growth without division, which presents as macrocytosis. Megaloblastic anemia has a rather slow onset, especially when compared to that of other anemias. The defect in red cell DNA synthesis is most often due to hypovitaminosis , specifically vitamin B12 deficiency or folate deficiency .
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Several studies have shown that bacterium can easily enter intestinal lumen through transcytosis of goblet cells. [7] Other studies, however, are exploring the idea that transcytosis may play a role in allowing medications to cross the blood-brain barrier. Exploiting this fact may allow certain drug therapies to be better utilized by the brain. [8]