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Microvilli (sg.: microvillus) are microscopic cellular membrane protrusions that increase the surface area for diffusion and minimize any increase in volume, [1] and are involved in a wide variety of functions, including absorption, secretion, cellular adhesion, and mechanotransduction.
Intestinal villi (sg.: villus) are small, finger-like projections that extend into the lumen of the small intestine.Each villus is approximately 0.5–1.6 mm in length (in humans), and has many microvilli projecting from the enterocytes of its epithelium which collectively form the striated or brush border.
The epithelial cells which line these villi have microvilli. The transport of nutrients across epithelial cells through the jejunum and ileum includes the passive transport of sugar fructose and the active transport of amino acids, small peptides, vitamins, and most glucose. The villi in the jejunum are much longer than in the duodenum or ileum.
Drawing showing the relationship between villi and microvilli of the small intestine. The luminal surface of the enterocytes have microvilli (1 micrometer long) while the cell layer itself is folded to form villi (0.5-1.6 millimeters long) and crypts. Both serve to increase the total absorption surface of the intestine.
Microvilli on the apical surface increase its surface area. This facilitates transport of numerous small molecules into the enterocyte from the intestinal lumen . These include broken down proteins , fats , and sugars , as well as water, electrolytes , vitamins , and bile salts .
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