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Trimix is available in several different formulations, including a gel that can be used topically, a gel that can be administered into the urethra, and an injectable form that is administered via intracavernosal injection (an injection at either side, not the base, of the penis). [2] [4] [5] [6]
An intracavernous (or intracavernosal) injection is an injection into the base of the penis.This injection site is often used to administer medications to check for or treat erectile dysfunction in adult men (in, for example, a combined intracavernous injection and stimulation test). [1]
When injected into the penis for erectile dysfunction; side effects may include penile pain, bleeding at the site of injection, and prolonged erection (priapism). [2] Prostaglandin E 1 is in the vasodilator family of medications. [2] It works by opening blood vessels and relaxing smooth muscle. [2]
Combined intracavernous injection and stimulation test or CIS test is the most commonly performed office diagnostic procedure for erectile dysfunction. It consists of an intracavernosal injection , visual or manual sexual stimulation , and a rating of the subsequent erection .
Alprostadil injections as a vasodilator are also used for the treatment of erectile dysfunction, expanding blood vessels that result in increasing blood flow to the penis. [72] For females, vaginal lubricant production can be increased by hormone replacement therapy (HRT) medicine such as vaginal estrogen. [73]
Venous leak, also called venogenic erectile dysfunction and penile venous insufficiency, is one category of vasculogenic impotence — a cause of erectile dysfunction in males. [2] It affects all ages, being particularly awkward in young men. [ 3 ]
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