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Gut microbiota, gut microbiome, or gut flora are the microorganisms, including bacteria, archaea, fungi, and viruses, that live in the digestive tracts of animals. [ 1 ][ 2 ] The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. [ 3 ][ 4 ] The gut is the main location of the human microbiome. [ 5 ]
Fecal microbiota transplant (FMT), also known as a stool transplant, [2] is the process of transferring fecal bacteria and other microbes from a healthy individual into another individual. FMT is an effective treatment for Clostridioides difficile infection (CDI). [3][4][5] For recurrent CDI, FMT is more effective than vancomycin alone, and may ...
The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation. [1][2] The effect is most associated with orally administered ...
Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. [3][4] It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. [3] It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. [1][2]
Glucokinase in beta cells serves as a glucose sensor, amplifying insulin secretion as blood glucose rises. In the pancreatic beta-cell, glucokinase is a key regulator enzyme. Glucokinase is very important in the regulation of insulin secretion and has been known as the pancreatic beta-cell sensor.
Fructose malabsorption. Fructose malabsorption, formerly named dietary fructose intolerance (DFI), is a digestive disorder [1] in which absorption of fructose is impaired by deficient fructose carriers in the small intestine's enterocytes. This results in an increased concentration of fructose.
Since dogs can’t speak like humans, they’re all about the body language. If you want to understand your dog’s needs and emotions better, be observant when it comes to this form of communication.
Fructose 2,6-bisphosphate, abbreviated Fru-2,6-P2, is a metabolite that allosterically affects the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1) to regulate glycolysis and gluconeogenesis. [1] Fru-2,6- P2 itself is synthesized and broken down in either direction by the integrated bifunctional ...