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Spironolactone can cause breast pain and breast enlargement in women. [ 128 ] [ 129 ] This is "probably because of estrogenic effects on target tissue." [ 111 ] At low doses, breast tenderness has been reported in only 5% of women, but at high doses, it has been reported in up to 40% of women.
A 1991 review reported that the influences of spironolactone on androgen levels in women were variable and inconsistent. [78] Spironolactone has shown no significant effect on levels of testosterone, estradiol, luteinizing hormone, and follicle-stimulating hormone in men. [146] [78]
Side effects often could not be unambiguously attributed to spironolactone due concomitant use of other medications, particularly birth control pills. Hyperkalemia was rare (14/469; 3.0%) and was "invariably mild and clinically insignificant". Risk of bias was high and quality of evidence was low to very low. Sources: [1]
Spironolactone is an acne treatment prescribed by dermatologists. Find out how spironolactone improves the appearance of hormonal acne, side effects, and more. Everything I Wish I Knew About ...
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Sweating might occur all over your body or in specific spots, like your palms, feet, face, or armpits. There’s no cure for the condition, but it can be treated with medications or special ...
Hyperandrogenism is a medical condition characterized by high levels of androgens.It is more common in women than men. [4] Symptoms of hyperandrogenism may include acne, seborrhea, hair loss on the scalp, increased body or facial hair, and infrequent or absent menstruation.
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...