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Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, ...
every morning: quaque ante meridiem q.d., qd every day / daily quaque die q.h.s., qhs every night at bedtime quaque hora somni q.d.s, qds, QDS 4 times a day quater die sumendum q.i.d, qid 4 times a day quater in die q.h., qh every hour, hourly quaque hora q.o.d., qod every other day / alternate days quaque altera die q.p.m., qPM, qpm
tomorrow morning c.m.s. cras mane sumendus: to be taken tomorrow morning c̄, c. cum: with (usually written with a bar on top of the c) cib. cibus: food c.c. cum cibo: with food [or] cubic centimetre: mistaken for U, meaning units; also has an ambiguous meaning; use "mL" or "millilitres" (1 cm 3 = 1 mL) cf. confer compare c.n. cras nocte
[12] [13] Due to its activity as an androgen receptor antagonist and progesterone receptor agonist, spironolactone causes adverse effects, including gynecomastia or decreased libido in males and menstrual abnormalities in females. [14] Spironolactone also causes hyperkalemia [15] and renal insufficiency. [16]
Alternatively, if you usually skip lunch or eat light dinners, taking metformin in the morning after breakfast could work best. Stomach and bowel issues can be metformin side effects, especially ...
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Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]