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Rh o (D) immune globulin (RhIG) is a medication used to prevent RhD isoimmunization in mothers who are RhD negative and to treat idiopathic thrombocytopenic purpura (ITP) in people who are Rh positive. [2] It is often given both during and following pregnancy. [2] It may also be used when RhD-negative people are given RhD-positive blood. [2]
[1] [2] [3] Pollack co-developed the vaccine, also known by the RhoGAM brand name, which is given to pregnant women to prevent Rh disease, with Dr. Vincent Freda and Dr. John G. Gorman of Columbia-Presbyterian Medical Center. [1] Pollack's vaccine, introduced in 1968, virtually eliminated cases of Rh disease in developed countries. [1]
The protection that is offered today against Rh incompatibility involved preventive measures that primarily utilize Rh immunoglobulin, also known as RhoGAM. [13] The aim of these treatments are to prevent the mother’s immune system from becoming sensitized to the Rh antigen, which reduces the risk of hemolytic disease in future pregnancies.
The name rhesus factor (Rh) goes back to the use of erythrocytes extracted from the blood of rhesus monkeys for obtaining the first blood serum. The Rh blood group system is a human blood group system. It contains proteins on the surface of red blood cells. After the ABO blood group system, it is most likely to be involved in transfusion reactions.
John Grant Gorman AC, (born c. 1931) [1] is an Australian physician and medical researcher. In 1980, Gorman shared the Lasker-DeBakey Clinical Medical Research Award for pioneering work on the rhesus blood group system, the role of rhesus D antibodies in the causation of Rh disease and the apparently paradoxical prevention of Rh disease using the Rh antibodies themselves, in the form of Rho(D ...
Medications can be used to prevent cancer in a few circumstances. [145] In the general population, NSAIDs reduce the risk of colorectal cancer; however, due to cardiovascular and gastrointestinal side effects, they cause overall harm when used for prevention. [146] Aspirin has been found to reduce the risk of death from cancer by about 7%. [147]
In some cases, chemoprophylaxis is initiated to prevent the spread of an existing infection in an individual to a new organ system, as when intrathecal chemotherapy is administered in patients with malignancy to prevent further infection. The use of chemoprophylaxis is limited primarily by two factors: risk and financial costs.
In many developing countries cancer incidence, insofar as this can be measured, appears much lower, most likely because of the higher death rates due to infectious disease or injury. With the increased control over malaria and tuberculosis in some Third World countries, incidence of cancer is expected to rise.