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According to Henry Gray's estimates, the palm has around 370 sweat glands per cm 2; the back of the hand has 200 per cm 2; the forehead has 175 per cm 2; the breast, abdomen, and forearm have 155 per cm 2; and the back and legs have 60–80 per cm 2. [2] In the finger pads, sweat glands pores are somewhat irregularly spaced on the epidermal ridges.
Hands, feet, armpits, groin, and the facial area are among the most active regions of perspiration due to the high number of sweat glands (eccrine glands in particular) in these areas. When excessive sweating is localized (e.g. palms, soles, face, underarms, scalp) it is referred to as primary hyperhidrosis or focal hyperhidrosis.
Focal hyperhidrosis, also known as primary hyperhidrosis, is a disease characterized by an excessive sweating localized in certain body regions (particularly palms, feet and underarms). Studies suggest that this condition, affecting between 1% and 3% of the US population, seems to have a genetic predisposition in about two thirds of those affected.
Palmoplantar hyperhidrosis is excessive sweating localized to the palms of the hands and soles of the feet. It is a form of focal hyperhidrosis in that the excessive sweating is limited to a specific region of the body. As with other types of focal hyperhidrosis (e.g. axillary and craniofacial) the sweating tends to worsen during warm weather. [1]
A few other major signs to look out for include extreme fatigue, headaches, fever, a butterfly-shaped rash across the cheeks and nose, hair loss, and Raynaud’s phenomenon (a condition in which ...
The eccrine sweat glands are distributed over much of the body and are responsible for secreting the watery, brackish sweat most often triggered by excessive body temperature. Apocrine sweat glands are restricted to the armpits and a few other areas of the body and produce an odorless, oily, opaque secretion which then gains its characteristic ...
Eccrine sweat glands are found in virtually all skin, with the highest density in the palms of the hands, and soles of the feet, and on the head, but much less on the torso and the extremities. In other mammals, they are relatively sparse, being found mainly on hairless areas such as foot pads.
Acquired idiopathic generalized anhidrosis appears to have a variety of etiologies. Theoretically, dysfunction or degeneration of cholinergic sympathetic nerve fibers involved in sweating (sudomotor neuropathy), dysfunction of acetylcholine receptors and/or cholinergic signals (idiopathic pure sudomotor failure may fall under this category), and primary failures of the sweat glands with ...